| Date | Location | Result | |
| 11/27/10 | Belton, Texas | Mary Hardin-Baylor 69, Thomas More 7 | Box score |
| 11/20/10 | Crestview Hills, Ky. | Thomas More 42, Washington & Lee 14 | Box score |
| 10/13/10 | Crestview Hills, Ky. | Thomas More 33, Mount St. Joseph 0 | Box score |
| 11/06/10 | Waynesburg, Pa. | Thomas More 14, Waynesburg 10 | Box score |
| 10/30/10 | Crestview Hills, Ky. | Thomas More 37, Westminster 13 | Box score |
| 10/23/10 | Bethany, W.Va. | Thomas More 48, Bethany 14 | Box score |
| 10/16/10 | Crestview Hills, Ky. | Thomas More 24, Saint Vincent 6 | Box score |
| 10/09/10 | Grove City, Pa. | Thomas More 31, Grove City 9 | Box score |
| 10/02/10 | Crestview Hills, Ky. | Thomas More 42, Thiel 3 | Box score |
| 09/25/10 | Crestview Hills, Ky. | Thomas More 29, Wash. & Jefferson 21 | Box score |
| 09/18/10 | Beaver Falls, Pa. | Thomas More 36, Geneva 20 | Box score |
| 09/11/10 | Hanover, Ind. | Thomas More 56, Hanover 12 | Box score |